Screening of erm Gene of Inducible Clindamycin Resistant Staphylococcus aureus
نویسندگان
چکیده
منابع مشابه
Differences in potential for selection of clindamycin-resistant mutants between inducible erm(A) and erm(C) Staphylococcus aureus genes.
In staphylococci, inducible macrolide-lincosamide-streptogramin B (MLS(B)) resistance is conferred by the erm(C) or erm(A) gene. This phenotype is characterized by the erythromycin-clindamycin "D-zone" test. Although clindamycin appears active in vitro, exposure of MLS(B)-inducible Staphylococcus aureus to this antibiotic may result in the selection of clindamycin-resistant mutants, either in v...
متن کاملPrevalence of clindamycin-resistant Staphylococcus aureus induced by macrolide resistance
Introduction: Since the incidence of various infections caused by Staphylococcus aureus increases, the use of effective antibiotics such as clindamycin has been growing to treat the systemic and local infections caused by such organisms. Antibiotic-resistant species are emerging and spreading in today's communities due to misuse of antibiotics and incomplete treatment, turning into a serious ch...
متن کاملInducible clindamycin resistance in clinical isolates of Staphylococcus aureus due to erm genes, Iran
BACKGROUND AND OBJECTIVES Resistance to macrolide can be mediated by erm and msrA genes in Staphylococcus aureus. There are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. The aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msrA genes among S. aureus isolates. M...
متن کاملFailure of clindamycin treatment of methicillin-resistant Staphylococcus aureus expressing inducible clindamycin resistance in vitro.
We report a case of a surgical site infection caused by clindamycin-susceptible, erythromycin-resistant methicillin-resistant Staphylococcus aureus (MRSA) that did not respond to treatment with clindamycin. The MRSA isolate obtained after treatment was resistant to clindamycin but was found to be identical by pulsed-field gel electrophoresis to the clindamycin-susceptible isolate obtained befor...
متن کاملinducible clindamycin resistance in clinical isolates of staphylococcus aureus due to erm genes, iran.
background and objectives: resistance to macrolide can be mediated by erm and msra genes in staphylococcus aureus . there are the evidences that show erm genes may be causative agent of inducible or constitutive resistance. the aim of this study was to investigate the incidence of inducible clindamycin resistance and determine the most frequency of erm and msr a genes among s. aureus isolates. ...
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ژورنال
عنوان ژورنال: Journal of Institute of Science and Technology
سال: 2019
ISSN: 2467-9240
DOI: 10.3126/jist.v24i2.27255